HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-6-(2-pyridylmethoxy)pyrimidine → 6-(2-Pyridylmethoxy)pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-6-(2-pyridylmethoxy)pyrimidine | HCID 20230156 | — |
| Reactant | 4-(2-Chlorophenyl)-3-ethoxycarbonyl-2-(2-hydroxyethoxymethyl)-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine | HCID 70353567 | — |
| Product | 6-(2-Pyridylmethoxy)pyrimidine | HCID 20230160 | — |
Reaction Steps
4-<2-{[4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyrid-2-yl]methoxy}ethoxy>-6-(2-pyridylmethoxy)pyrimidine was prepared by the method described in Example 13 using 4-(2-chlorophenyl)-3-ethoxycarbonyl-2-(2-hydroxyethoxymethyl)-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine and 4-chloro-6-(2-pyridylmethoxy)pyrimidine as the starting materials. The product had m.p. 64°-67° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04618609 |
| Source dataset | uspto-grants-1986_10 |
| ORD ID | ord-994cc87fa936424f96ddfed1530954ac |
| Source note | uspto-grants-1986_10 |