HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-6-(1-methyl-2-imidazolylmethoxy)pyrimidine → 6-(1-Methyl-2-imidazolylmethoxy)pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-6-(1-methyl-2-imidazolylmethoxy)pyrimidine | HCID 20230154 | — |
| Reactant | 4-(2-Chlorophenyl)-3-ethoxycarbonyl-2-(2-hydroxyethoxymethyl)-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine | HCID 70353567 | — |
| Product | 6-(1-Methyl-2-imidazolylmethoxy)pyrimidine | HCID 86741076 | — |
Reaction Steps
4-<2-{[4-(2-Chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyrid-2-yl]methoxy}ethoxy>-6-(1-methyl-2-imidazolylmethoxy)pyrimidine was prepared by the method described in Example 13 using 4-chloro-6-(1-methyl-2-imidazolylmethoxy)pyrimidine and 4-(2-chlorophenyl)-3-ethoxycarbonyl-2-(2-hydroxyethoxymethyl)-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine as the starting materials. The product had m.p. 48°-51° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04618609 |
| Source dataset | uspto-grants-1986_10 |
| ORD ID | ord-7fc5356fcba34726b175f0018f64f52d |
| Source note | uspto-grants-1986_10 |