Ebselen → HCID 18604983, compound

Participants

Reaction Steps

2,74 g (10 mmol) 2-phenyl-1,2-benzoisoselenazole-3(2H)-one and 1,21 g (10 mmol) L-cysteine are dissolved in 25 ml trifluororacetic acid. This solution is stirred for 18 hours at room temperature. Then, 150 ml of an ice-water mixture are added to this solution. The deposited precipitate after some stirring becomes solid. It is sucked off and finally dissolved in methanol. After evaporation of the solvent, a residue remains which is washed with ether.

Provenance & Evidence