Hydrochloric Acid → HCID 54443319, compound

HRID 2290825Notes

Reaction equation

HRID 2290825 reaction equation
C([O:4][C:5]1[CH:6]=[C:7]([CH:15]=[CH:16][C:17](=[O:24])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH:8]=[CH:9][C:10]=1[O:11]C(=O)C)(=O)C.[OH-].[Na+].O.Cl>CO>[OH:4][C:5]1[CH:6]=[C:7]([CH:15]=[CH:16][C:17](=[O:24])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[CH:8]=[CH:9][C:10]=1[OH:11]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 14798Sodium HydroxideHCID 54093623HCID 54093623, compound

Product 1

HCID 54443319HCID 54443319, compoundYield 93.5%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

In 10 ml of methanol was dissolved 830 mg of 1-(3,4-diacetoxyphenyl)-1-nonen-3-one and after adding 7.5 ml of an aqueous 1N-sodium hydroxide solution to the solution, the mixture was stirred for 30 minutes at room temperature. Then, the reaction mixture was ice-cooled and after adding thereto 25 ml of water, the mixture was acidified with the addition of 5 ml of an aqueous 1N-hydrochloric acid solution to form crystals, which were collected by filtration and washed with water to provide 580 mg of 1-(3,4-dihydroxyphenyl)-1-nonen-3-one.

Workup

  1. temperaturecooled
  2. additionafter adding
  3. customto form crystals, which
  4. filtrationwere collected by filtration
  5. washwashed with water

Sources & evidence

ORD record
ord-89f717d75eec4f16b5524455eeb6bfaa
Source dataset
uspto-grants-1986_10
Patent number
US04618627

Reaction notes

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