Iodoethane → HCID 20230733, compound

HRID 2290933Notes

Reaction equation

[CH2:1]([C:3]1[C:8]2[CH:9]3[CH:13]([CH2:14][CH2:15][C:7]=2[C:6]([O:18][CH3:19])=[C:5]([O:20][CH3:21])[CH:4]=1)[C:12](=[O:16])[NH:11][C:10]3=[O:17])[CH3:2].[CH2:22](I)[CH3:23]>>[CH2:22]([N:11]1[C:10](=[O:17])[CH:9]2[CH:13]([CH2:14][CH2:15][C:7]3[C:6]([O:18][CH3:19])=[C:5]([O:20][CH3:21])[CH:4]=[C:3]([CH2:1][CH3:2])[C:8]=32)[C:12]1=[O:16])[CH3:23]

Participants

Reactant 2

HCID 6340Iodoethane

HCID 20230708HCID 20230708, compound

Product 1

HCID 20230733HCID 20230733, compound

Procedure

Using the procedure as in example 64, but starting with 9-ethyl-3a,4,5,9b-tetrahydro-6,7-dimethoxy-1H-benz[e]isoindole-1,3-(2H)-dione, and ethyl iodide in place of methyl iodide afforded the desired compound.

Sources & evidence

ORD record: ord-12de3fc1ffe348e08b6ce01dfdc7e40f
Source dataset: uspto-grants-1986_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04618683

Reaction notes

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