反应详情

To a stirred solution of 5.16 g. of N-(2-hydroxyethyl)-2-oxo-pyrrolidine in 200 ml. of anhydrous tetrahydrofuran at room temperature was added 4.48 g. of potassium t-butoxide. A gummy precipitate formed. The mixture was stirred for 1 hour, and then 3.6 ml. of carbon disulfide was added. The mixture was stirred for 2 hours, and then 100 ml. of anhydrous ether was added, causing the formation of a gummy precipitate. The solvent was decanted from the gummy precipitate, and the gummy precipitate was dried under high vacuum to give a foam (5.0 g.) of the title compound.

1. customA gummy precipitate formed
2. stirringThe mixture was stirred for 2 hours
3. customThe solvent was decanted from the gummy precipitate
4. customthe gummy precipitate was dried under high vacuum