Potassium Hydroxide → HCID 178516724, compound

HRID 2291103Notes

Reaction equation

HRID 2291103 reaction equation
O.NN.[Cl:4][C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][CH:14]=1)[N:11]=[C:10]([OH:15])[CH:9]=[N+:8]2[O-].[OH-].[K+]>>[Cl:4][C:5]1[CH:6]=[C:7]2[C:12](=[CH:13][CH:14]=1)[N:11]=[C:10]([OH:15])[CH:9]=[N:8]2

Participants

4

Reactant 3

HCID 14797Potassium HydroxideHCID 24654Hydrazine hydrate (1:1)HCID 1785262836-Chloro-2-quinoxalinol-4-oxide

Product 1

HCID 178516724HCID 178516724, compoundYield 96%

Procedure

The treated catalyst (I) (containing 0.3 g of metallic nickel) and 4.0 g of a 80% aqueous hydrazine hydrate solution were added dropwise to 240 g of an aqueous solution containing 19.7 g of 6-chloro-2-quinoxalinol-4-oxide and 28 g of potassium hydroxide at 40° to 50° C., and the reaction was carried out at 40° to 80° C. for 5 hr. After the catalyst was removed, the filtrate was acidified to give 17.3 g (yield 96%) of 6-chloro-2-quinoxalinol.

Workup

  1. customAfter the catalyst was removed

Sources & evidence

ORD record
ord-108a337bedb14ab387896109d6bf5a2c
Source dataset
uspto-grants-1986_10
Patent number
US04620003

Reaction notes

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