HRID2291287

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66057

2-Methylpiperazine

C5H12N2

结构：CCOC(=O)Nc1c(F)c(F)c(F)c2c1c(=O)c(C(=O)OCC)cn2C1CC1

HCID15729400

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)Nc1c(F)c(N2CCNC(C)C2)c(F)c2c1c(=O)c(C(=O)OCC)cn2C1CC1

HCID21279709

未命名化合物

PROCEDURE

实验过程

In the same manner as described in Example 1 (1), ethyl 1-cyclopropyl-5-ethoxycarbonylamino-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate (m.p. 189°-190° C.) was allowed to react with 2-methylpiperazine to give ethyl 1-cyclopropyl-5-ethoxycarbonylamino-6,8-difluoro-7-(3-methyl-1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylate.