Imidazole → HCID 23042688, compound

HRID 2291310Notes

Reaction equation

HRID 2291310 reaction equation
Br[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:22]=[CH:21][C:9]([O:10][CH2:11][CH2:12][CH2:13][C:14]([CH3:20])([CH3:19])[C:15]([O:17][CH3:18])=[O:16])=[CH:8][CH:7]=1.[OH:23][C:24]1[CH:25]=[N:26][CH:27]=[CH:28][CH:29]=1.Br[CH2:31]CCOC1C=CC(OCCCCCC(C)(C)C(OC)=O)=CC=1.N1C=CN=C1>>[CH3:19][C:14]([CH3:20])([CH2:13][CH2:12][CH2:11][O:10][C:9]1[CH:21]=[CH:22][C:6]([O:5][CH2:4][CH2:3][CH2:2][O:23][C:24]2[CH:25]=[N:26][CH:27]=[CH:28][CH:29]=2)=[CH:7][CH:8]=1)[C:15]([O:17][CH2:18][CH3:31])=[O:16]

Participants

5

Reactant 4

HCID 795ImidazoleHCID 79713-HydroxypyridineHCID 13422029HCID 13422029, compoundHCID 13934406HCID 13934406, compound

Product 1

HCID 23042688HCID 23042688, compound

Procedure

Methyl 5-[p-(3-bromopropoxy)phenoxy]-2,2-dimethylpentanoate and 3-hydroxypyridine were used as starting compounds in place of methyl 7-[p-(3-bromopropoxy)phenoxy]-2,2-dimethylheptanoate and imidazole, respectively, in EXAMPLE 33. The starting compounds were reacted and treated in a manner similar to EXAMPLE 33 to give the desired product, ethyl 2,2-dimethyl-5-[p-[3-(3-pyridyloxy)propoxy]phenoxy]pentanoate, as an oily substance.

Workup

  1. customThe starting compounds were reacted
  2. additiontreated in a manner similar to EXAMPLE 33

Sources & evidence

ORD record
ord-9a6b7b3387fe4442a919bf4d1c55fc58
Source dataset
uspto-grants-1989_01
Patent number
US04795753

Reaction notes

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