Acetohydrazide → HCID 178475142, compound

Participants

Reaction Steps

A solution of methyl 5-[3-(2-[2,2,2-trifluoroethyl]guanidino)-1,2,4-triazol-1-yl]valerimidate (0.5 g.) in MeOH (5 ml.) and acethydrazide (0.17 g.) was allowed to stand at room temperature for 3 hours. The solution was evaporated to give a sticky solid which was triturated with ether/EtOH to give N-acetylamino-5-[3-(2-[2,2,2-trifluoroethyl]guanidino)-1,2,4-triazol-1-yl]valeramidine as a white solid (0.71 g.), m.p. 157°-159°.

Provenance & Evidence