HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 5-Bromo-4-chloro-6-phenylpyrimidin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 2-Amino-4-chloro-6-phenylpyrimidine | HCID 240802 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-Bromo-4-chloro-6-phenylpyrimidin-2-amine | HCID 14370057 | — |
Reaction Steps
To 1.5 g (7.3 mM) of 4-chloro-6-phenyl-2-pyrimidinamine is added 75 ml of glacial acetic acid. This mixture is stirred to dissolve and 0.44 ml of bromine is added. The reaction is stirred at ambient temperature for 24 hours. The solution is evaporated to dryness under vacuum to yield 1.75 g of 5-bromo-4-chloro-6-phenyl-2-pyrimidinamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04795812 |
| Source dataset | uspto-grants-1989_01 |
| ORD ID | ord-b39dacb255fa4c7fb341d9b2b46b86dc |
| Source note | uspto-grants-1989_01 |