Acetone → 4-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane

HRID 2291428Notes

Reaction equation

HRID 2291428 reaction equation
[Br:1][CH2:2][CH:3]([OH:6])[CH2:4][OH:5].S([O-])([O-])(=O)=O.[Mg+2].[CH3:13][C:14]([CH3:16])=O>>[CH3:13][C:14]1([CH3:16])[O:6][CH:3]([CH2:2][Br:1])[CH2:4][O:5]1

Participants

4

Reactant 3

HCID 180AcetoneHCID 208273-Bromo-1,2-propanediolHCID 24083Sulfuric acid magnesium salt (1:1)

Product 1

HCID 1697594-(Bromomethyl)-2,2-dimethyl-1,3-dioxolane

Procedure

An acetone solution of bromomethyl ethylene glycol is refluxed for 24 hours in the presence of anhydrous magnesium sulfate. The cooled reaction mixture is filtered and the solvent is removed to provide a residual crude product.

Workup

  1. customThe cooled reaction mixture
  2. filtrationis filtered
  3. customthe solvent is removed

Sources & evidence

ORD record
ord-1b8c97ef73d242aa8fe5027e9c600a21
Source dataset
uspto-grants-1989_01
Patent number
US04796976

Reaction notes

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