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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2291431Generated: November 3, 2026

Dimethylformamide → 4-[Bis[2-(acetyloxy)ethyl]amino]benzaldehyde

https://huagongshe.com/reaction/2291431

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantPhosphorus oxychlorideHCID 24813—
ReactantEthanol, 2,2'-(phenylimino)bis-, 1,1'-diacetateHCID 29521—
Product4-[Bis[2-(acetyloxy)ethyl]amino]benzaldehydeHCID 32872993%

Reaction Steps

N,N-Di-(2-acetoxyethyl)aniline (A6) (126 g, 0.476 mol) was reacted with phosphorous oxychloride (80.3 g, 0.524 mol) in DMF as for A2 in Example 3. The product was distilled at 155°-175° C. (0.15 mm) to yield 130 g (93%) of A7 as an orange oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04796971
Source datasetuspto-grants-1989_01
ORD IDord-05a49bd50ddd4a34b18906cf3394db88
Source noteuspto-grants-1989_01