2-Acetamidomethyl-4-nitrophenol → HCID 21278599, compound

HRID 2291435Notes

Reaction equation

HRID 2291435 reaction equation
[C:1]([NH:4][CH2:5][C:6]1[CH:11]=[C:10]([N+:12]([O-])=O)[CH:9]=[CH:8][C:7]=1[OH:15])(=[O:3])[CH3:2]>C(O)C.[H][H].[Pt]>[C:1]([NH:4][CH2:5][C:6]1[CH:11]=[C:10]([NH2:12])[CH:9]=[CH:8][C:7]=1[OH:15])(=[O:3])[CH3:2]

Participants

5

Reactant 1

HCID 3351402-Acetamidomethyl-4-nitrophenol

Product 1

HCID 21278599HCID 21278599, compound

Reagents, catalysts & solvents 3

HCID 23939PlatinumCatalystHCID 702EthanolSolventHCID 178418361HCID 178418361, compoundSolvent

Procedure

2.3 g (0.012 mole) of the nitro compound of step 3 is dissolved in ethanol and hydrated with hydrogen using a platinum catalyst. After absorbing the theoretical quantity of hydrogen the catalyst is suction filtered off, acidified with hydrochloric acid, and the solvent is evaporated in a vacuum. The compound forms a non-crystallizing oil.

Workup

  1. customAfter absorbing the theoretical quantity of hydrogen the catalyst
  2. filtrationfiltered off
  3. customthe solvent is evaporated in a vacuum

Sources & evidence

ORD record
ord-52dab8b67b17490881b694240efe3992
Source dataset
uspto-grants-1989_01
Patent number
US04797130

Reaction notes

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