Dimethylformamide dimethyl acetal → HCID 15595573, compound

Participants

Reaction Steps

55.1 g (0.25 mole) of 7-chloro-3-methylquinoline-8-carboxamide were dissolved in 50 ml of N,N-dimethylformamide, 39.3 g (0.32 mole) of N,N-dimethylformamide dimethyl acetal were added, and the mixture was refluxed for 4 hours. After precipitation on ether, 44.0 g (64%) of colorless crystals of melting point 183°-185° C. (decomposition) were isolated (compound No. 22).

Provenance & Evidence