反应详情

3,4-Dichloronitrobenzene (10 g), piperazine (30 g) and dioxan (10 ml) were stirred for 4 hours under gentle reflux (internal temp. 120°-130°). The mixture was then cooled and water (50 ml) was added; the desired product crystallized out and was filtered off, washed with water and dried: yield of the compound 11.32 g. A small portion (0.6 g) was recrystallized from petroleum b.p. 60°-80°/ethyl acetate, yielding the product, (0.36 g), m.p. 100°-102°.

1. temperatureunder gentle reflux (internal temp. 120°-130°)
2. temperatureThe mixture was then cooled
3. customthe desired product crystallized out and
4. filtrationwas filtered off
5. washwashed with water
6. customdried
7. customA small portion (0.6 g) was recrystallized from petroleum b.p. 60°-80°/ethyl acetate
8. customyielding the product, (0.36 g), m.p. 100°-102°