反应详情

Diphenylcarbamic chloride (23 g, 0.1 mol, Aldrich Chemical Co., Milwaukee, Wis., U.S.A.) was added to a solution of 10.1 g of triethylamine and 9.3 g (0.1 mol) of benzeneamine in 150 ml of chloroform. The resulting solution was heated under reflux overnight. The solution was cooled to room temperature and washed three times with 100-ml portions of brine solution, dried over anhydrous magnesium sulfate, and evaporated to give an off-white solid which was triturated with diethyl ether to give triphenylurea as a white solid, mp 136°-138° C.

1. temperatureThe resulting solution was heated
2. temperatureunder reflux overnight
3. washwashed three times with 100-ml portions of brine solution
4. dry with materialdried over anhydrous magnesium sulfate
5. customevaporated
6. customto give an off-white solid which
7. customwas triturated with diethyl ether