Formaldehyde → 2-{[Bis(2-hydroxyethyl)amino]methyl}-4,6-dibromophenol

Participants

Reaction Steps

252 g of 2,4-dibromophenol and 105 g of diethanolamine were charged to a 1 liter round-bottomed flask fitted with an agitator. The temperature of the clear viscous liquid was adjusted to 40 Deg. C. and 100 g of formalin (30% formaldehyde in water stabilised with methanol) was added dropwise over 1 hour while maintaining the temperature at 40-45 Deg C. The temperature was then raised to 100-110 Deg. C. and maintained at that temperature for 4 hours. Vacuum was then applied to distil off excess formaldehyde, methanol and water.

Provenance & Evidence