Methyl 3-(4-chlorophenyl)-2,2dimethoxypropionate → Methyl 3-(4-chlorophenyl)propanoate

Participants

Reaction Conditions

Reaction Steps

A mixture of methyl 3-(4-chlorophenyl)-2,2dimethoxypropionate (6.09 g) and formic acid (27 ml) was heated at 65 to 70° C. for 4 hours with stirring. The reaction mixture was cooled and extracted with methylene chloride. The extract was washed with water, dried over magnesium sulfate and evaporated in vacuo to give methyl 3-(4-chlorophenyl)propionate.

Provenance & Evidence