Isobutyl 3,4-epoxybutyrate → HCID 86742670, compound

Participants

Reaction Steps

A mixture of 0.7 g 2-phenylimidazolidine-4-one and 1 g 2-methylpropyl 3,4-epoxybutanoate are heated for 12 h at 70° (external temperature) in 2 ml water and 2 ml acetone. After evaporating, the residue is taken up with ether and the white solid obtained is filtered, and recrystallised from ethyl/acetate, 2-Methylpropyl-2-phenyl-4-oxoimidazolidine-β-hydroxybutanoate is obtained as a white powder, m.p. 126°-128° C.

Provenance & Evidence