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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2291703Generated: November 1, 2026

N'-hydroxy-2-phenylethanimidamide → 5-Pentafluoroethyl-4-phenyl-3-aminoisoxazole

https://huagongshe.com/reaction/2291703

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN'-hydroxy-2-phenylethanimidamideHCID 2731007—
Reactanttert-Butyl pentafluoropropionateHCID 2773453—
Product5-Pentafluoroethyl-4-phenyl-3-aminoisoxazoleHCID 15613906—

Reaction Steps

The title compouhd was obtained according to the same procedure as described in Example 32 except that phenylacetoamide oxime (1.50 g, 0.0100 mole) and t-butyl pentafluoropropionate (6.66 g, 0.0300 mole) were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04797492
Source datasetuspto-grants-1989_01
ORD IDord-fe478da9e98a4737b8e28104d204f796
Source noteuspto-grants-1989_01