HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-(Trifluoromethyl)isoxazol-3-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-Dimethylcarbamoylamino-5-trifluoromethylisoxazole | HCID 15613849 | — |
| Product | 5-(Trifluoromethyl)isoxazol-3-ylamine | HCID 15613879 | — |
Reaction Steps
A mixture of 5-trifluormethyl-3-dimethylcarbamoylaminoisoxazole (1.15 g, 0.005 mole) and 36% hydrochloric acid (10 eq.) were reacted at 100° C. for 10 hours. The reaction mixture was worked up in the usual way to give the crude title compound. Crude yield: 0.20 g (26%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04797492 |
| Source dataset | uspto-grants-1989_01 |
| ORD ID | ord-53447d87f32b4ca29ed4f5a1e8e043b8 |
| Source note | uspto-grants-1989_01 |