Hexane → HCID 23711213, compound

Participants

Reaction Steps

0.50 g (1.18 mmoles) of 3-[9-(4-acetyl-3-hydroxy-2-n-propylphenoxymethyl)-4-oxo-pyrido[1,2-a]pyrimidin-3yl]propionic acid was suspended in 20 ml of ethanol, and 3.90 ml (1.18 mmoles) of a 2% ethanolic solution of potassium hydroxide was added thereto. This suspension was stirred until a clear solution was obtained. To the resulting reaction solution was added a small amount of n-hexane. The solid matter which separated out was collected by filtration and then dried to obtain 0.40 g (73% yield) of 3-[9-(4-acetyl-3-hydroxy-2-n-propyl-phenoxymethyl)-4-oxo-pyrido[1,2-a]pyrimidin-3-yl]propionic acid potassium salt in the form of white powder.

Provenance & Evidence