HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfoxide → HCID 14326855, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | HCID 19796336 | HCID 19796336 | — |
| Reactant | HCID 21278385 | HCID 21278385 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14326855 | HCID 14326855 | — |
Reaction Steps
Substantially the same procedures as in Example 1 were repeated except that 2.64 g of 1-isoquinolinesulfonyl chloride hydrochloride was used in place of 6.0 g of 1-chloro-5-isoquinolinesulfonyl chloride hydrochloride and that 2.22 g of the thus obtained 1-(5-isoquinolinesulfonyl)-3-hydroxypyrrolidine was reacted in dichloromethane with 1.08 g of oxalyl chloride and 0.67 g of dimethylsulfoxide. There was obtained 1-(5-isoquinolinesulfonyl)-3-pyrrolidone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04798897 |
| Source dataset | uspto-grants-1989_01 |
| ORD ID | ord-924bc5ae27194198a9520ee1f366020a |
| Source note | uspto-grants-1989_01 |