Hydrochloric Acid → HCID 13934066, compound

HRID 2291958Notes

Reaction equation

HRID 2291958 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[S:5]([C:8]1[C:9]2[CH:10]=[CH:11][N:12]=[CH:13][C:14]=2[CH:15]=[CH:16][CH:17]=1)(=[O:7])=[O:6].[ClH:24]>O>[ClH:24].[NH2:1][CH2:2][CH2:3][N:4]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH3:23])[S:5]([C:8]1[C:9]2[CH:10]=[CH:11][N:12]=[CH:13][C:14]=2[CH:15]=[CH:16][CH:17]=1)(=[O:7])=[O:6]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 13934065HCID 13934065, compound2×

Product 1

HCID 13934066HCID 13934066, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 1.34 g of N-(2-aminoethyl)-N-hexyl-5-isoquinolinesulfonamide [Compound (4)] was added 100 ml of water. Then, the pH of the solution was adjusted to 5 with hydrochloric acid. The mixture was lyophilized to obtain a residue. The residue thus obtained was subjected to recrystallization using a mixture consisting of 5% by weight of ethanol and 95% by weight of acetone to obtain 0.7 g of N-(2-aminoethyl)-N-hexy-5-isoquinolinesulfonamide hydrochloride. This compound was analyzed to give the following data.

Workup

  1. customto obtain a residue
  2. customThe residue thus obtained
  3. customwas subjected to recrystallization

Sources & evidence

ORD record
ord-5d91534d04524d8290f5a729cf908193
Source dataset
uspto-grants-1989_01
Patent number
US04798897

Reaction notes

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