HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 21277812, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (5-Bromo-1-benzofuran-2-yl)(4-chlorophenyl)methanol | HCID 3067877 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Cyclohexane | HCID 8078 | — |
| Product | HCID 21277812 | HCID 21277812 | — |
Reaction Steps
To 36.2 g of (5-bromobenzofuran-2-yl)(p-chlorophenyl)methanol dissolved in 50 ml of methylenchloride, 8.5 ml of thionylchloride in 25 ml of cyclohexane are added drop by drop, under agitation. After a 4 hour rest at 10° C., the solution is brought to dryness under vacuum condition. The residue is crystallized from petroleum ether: m.p. 83°-85° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04800208 |
| Source dataset | uspto-grants-1989_01 |
| ORD ID | ord-be99d0cd59cb413c8d2f4a1f665f4aba |
| Source note | uspto-grants-1989_01 |