Sulfur → HCID 13672415, compound

HRID 2292014Notes

Reaction equation

HRID 2292014 reaction equation
[CH3:1][C:2]1[NH:3][C:4](=[O:25])[CH2:5][S:6][C:7]=1[CH:8]1[CH:13]=[CH:12][N:11](C(OCC(Cl)(Cl)Cl)=O)[CH:10]=[C:9]1[C:22](=[O:24])[CH3:23].[S]>>[CH3:1][C:2]1[NH:3][C:4](=[O:25])[CH2:5][S:6][C:7]=1[C:8]1[CH:13]=[CH:12][N:11]=[CH:10][C:9]=1[C:22](=[O:24])[CH3:23]

Participants

3

Reactant 2

HCID 5362487SulfurHCID 13672423HCID 13672423, compound

Product 1

HCID 13672415HCID 13672415, compoundYield 7.8%

Procedure

A mixture of 5-methyl-6-[1-(2,2,2-trichloroethoxycarbonyl)-3-acetyl-1,4-dihydro-4-pyridinyl]-2H-1,4-thiazin-3(4H)-one (1.77 g) and sulfur sublimed (0.8 g) was treated in the same manner as described in Example 3 (ii) to give the titled compound (0.08 g, yield 7.8%) as pale yellow crystals. Ethyl acetate was used as a developing eluant.

Workup

  1. additionwas treated in the same manner

Sources & evidence

ORD record
ord-e492176c07ed4b9a9dd341502da744fe
Source dataset
uspto-grants-1989_01
Patent number
US04800201

Reaction notes

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