Sulfur → HCID 13672416, compound

HRID 2292015Notes

Reaction equation

HRID 2292015 reaction equation
[CH3:1][C:2]1[NH:3][C:4](=[O:28])[CH2:5][S:6][C:7]=1[CH:8]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]([O:18][CH3:19])[CH:16]=2)[N:11](C(OCC(Cl)(Cl)Cl)=O)[CH:10]=[CH:9]1.[S]>>[CH3:1][C:2]1[NH:3][C:4](=[O:28])[CH2:5][S:6][C:7]=1[C:8]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]([O:18][CH3:19])[CH:16]=2)[N:11]=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 5362487SulfurHCID 13672424HCID 13672424, compound

Product 1

HCID 13672416HCID 13672416, compoundYield 33%

Procedure

A mixture of 5-methyl-6-[1-(2,2,2-trichlorethoxycarbonyl)-6-methoxy-1,4-dihydro-4-quinolinyl]-2H-1,4-thiazin-3(4H)-one (0.6 g) and sulfur sublimed (0.3 g) was treated in the same manner as described in Example 3 (ii) to give the titled compound (0.12 g, yield 33%) as pale red crystals. Ethyl acetate was used as a developing eluant.

Workup

  1. additionwas treated in the same manner

Sources & evidence

ORD record
ord-91e277e6706f4220aaf676944360136d
Source dataset
uspto-grants-1989_01
Patent number
US04800201

Reaction notes

Loading…