Isopropylamine → HCID 70387113, compound

Participants

Reaction Steps

3.6 g (0.012 mol) of 1-methyl-6-bromo-1,2-dihydropyrido[4,3-c][1,8]naphthyridin-3(4H)-one, 30 ml of absolute ethanol and 10 ml of isopropylamine are stirred for 6 hours at 160° C. in an autoclave. After cooling, the crystalline precipitate is filtered off under suction and recrystallized from methanol. 2.82 g (87% of theory) of 1-methyl-6-isopropylamino-1,2-dihydropyrido-[4,3-c][1,8]naphthyridin-3(4H)-one are obtained.

Provenance & Evidence