4-Hydroxybenzophenone → 4-Benzoylphenyl 2-methylpropanoate

HRID 2292198Notes

Reaction equation

HRID 2292198 reaction equation
[OH:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:4][CH:3]=1.[C:16](Cl)(=[O:20])[CH:17]([CH3:19])[CH3:18]>N1C=CC=CC=1>[C:16]([O:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:14][CH:15]=1)(=[O:20])[CH:17]([CH3:19])[CH3:18]

Participants

4

Reactant 2

HCID 143474-HydroxybenzophenoneHCID 62325Isobutyryl chloride

Product 1

HCID 140103834-Benzoylphenyl 2-methylpropanoate

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

To a solution of 8.5 g of 4-hydroxybenzophenone in 75 ml of dry pyridine 6.75 ml of isobutyric chloride was added at 0°~10° C. The reaction mixture was allowed to stand at 25° C. for 2 h, poured into ice water. The precipitate was collected by suction and recrystallized from ethanol; M.P.~69°-69.5° C.

Workup

  1. customThe precipitate was collected by suction
  2. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-0a51b47ed3a84d12ac55f1188defee62
Source dataset
uspto-grants-1989_01
Patent number
US04801610

Reaction notes

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