N-Hydroxyphthalimide → HCID 131715829, compound

HRID 2292270Notes

Reaction equation

O[N:2]1[C:6](=[O:7])[C:5]2=[CH:8][CH:9]=[CH:10][CH:11]=[C:4]2[C:3]1=[O:12].Br[C:14]1[C:23]2[C:18](=[C:19]([C:24]([F:27])([F:26])[F:25])[CH:20]=[CH:21][CH:22]=2)[N:17]=[CH:16][CH:15]=1>>[F:27][C:24]([F:25])([F:26])[C:19]1[CH:20]=[CH:21][CH:22]=[C:23]2[C:18]=1[N:17]=[CH:16][CH:15]=[C:14]2[C:5]12[CH:8]=[CH:9][CH:10]=[CH:11][CH:4]1[C:3]([NH:2][C:6]2=[O:7])=[O:12]

Participants

Reactant 2

HCID 10665N-Hydroxyphthalimide

HCID 212773694-Bromo-8-(trifluoromethyl)quinoline

Product 1

HCID 131715829HCID 131715829, compound

Procedure

N-hydroxy-phthalimide and 4-bromo-8-trifluoromethylquinoline (a known compound) were reacted to obtain 0-(8-trifluoromethyl-4-quinolyl)-phthalimide which was reacted to obtain 0-(8-trifluoromethyl-4-quinolyl)-hydroxylamine melting at 152° C.

Sources & evidence

ORD record: ord-b3a5033878a74805b5bbfa7c1f934807
Source dataset: uspto-grants-1989_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04801717

Reaction notes

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