反应详情

A solution of 5.03 g (15.85 mmol) of 2-[[(3,4-dihydroxyphenyl)amino]carbonyl]hydrazinecarboxylic acid, phenylmethyl ester in 250 ml of methanol containing 2.64 ml (31.70 mmol) of hydrochloric acid was hydrogenated in the presence of 0.5 g of 10% palladium on charcoal for 5 minutes. The catalyst was filtered off and the solvent was distilled off in vacuo to leave a solid which was stirred with a few ml of dry ether; yield after drying in vacuo: 3.36 g; melting point 170°-180° C., dec.

1. filtrationThe catalyst was filtered off
2. distillationthe solvent was distilled off in vacuo
3. customto leave a solid which
4. customyield
5. customafter drying in vacuo