反应详情

A solution of 3.60 g (10.0 mmol) of 3,4-dihydroxybenzoic acid, 2-[[2-[(phenylmethoxy)carbonyl]hydrazino]carbonyl]hydrazide in 90 ml of dry methanol containing 1.67 ml (20.0 mmol) of concentrated hydrochloric acid was hydrogenated in the presence of 0.36 g of 10% palladium on charcoal for 15 minutes. After the removal of the catalyst by filtration and of the solvent by evaporation in vacuo, the crude solid (2.61 g) was stirred with a few ml of dry ether; yield: 2.41 g.

1. customAfter the removal of the catalyst
2. filtrationby filtration
3. customof the solvent by evaporation in vacuo