Phosphorus oxide (P4O10) → 2,3-Difluoro-1-octylbenzene

HRID 2292416Notes

Reaction equation

HRID 2292416 reaction equation
[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:9](O)[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>[Pd]>[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 2

HCID 14812Phosphorus oxide (P4O10)HCID 536998501-(2,3-Difluorophenyl)octan-1-ol

Product 1

HCID 144956292,3-Difluoro-1-octylbenzene

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Quantities: compound from Example 19 (53.3 g, 0.22 mol), phosphorus pentoxide (95 g, 0.67 mol) and 5% palladium-on-charcoal (5.5 g). The experimental procedure was as described in Example 22.

Sources & evidence

ORD record
ord-c569c470e2054be3a43919ece44e7e33
Source dataset
uspto-grants-1997_11
Patent number
US05683623

Reaction notes

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