Phosphorus oxide (P4O10) → 1-Decyl-2,3-difluorobenzene

HRID 2292418Notes

Reaction equation

HRID 2292418 reaction equation
[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:9](O)[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>[Pd]>[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

4

Reactant 2

HCID 14812Phosphorus oxide (P4O10)HCID 21477954(2,3-Difluorophenyl)decan-1-ol

Product 1

HCID 214779451-Decyl-2,3-difluorobenzene

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

Quantities: compound from Example 21 (56.4 g, 0.21 mol), phosphorus pentoxide (74.5 g, 0.53 mol) and 5% palladium-on-charcoal (4.58). The experimental procedure was as described in Example 22.

Sources & evidence

ORD record
ord-500d918177684402bdf015e9f0b33816
Source dataset
uspto-grants-1997_11
Patent number
US05683623

Reaction notes

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