Triisopropyl borate → HCID 21477963, compound

HRID 2292420Notes

Reaction equation

[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].C([Li])CCC.[B:20](OC(C)C)([O:25]C(C)C)[O:21]C(C)C>>[CH2:9]([C:3]1[CH:4]=[CH:5][C:6]([B:20]([OH:25])[OH:21])=[C:7]([F:8])[C:2]=1[F:1])[CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

Reactant 3

HCID 21531Triisopropyl borate

HCID 21477944HCID 21477944, compound

HCID 178418339Butyllithium

Product 1

HCID 21477963HCID 21477963, compound

Procedure

Quantities: compound from Example 23 (27.78, 0.14 mol), n-butyllithium (14 cm3, 10.0M in hexanes, 0.14 mol) and triisopropyl borate (52.7 g, 0.28 mol). The experimental procedure was as described in Example 28.

Sources & evidence

ORD record: ord-61d803b4215141fbbe53ca6e1aaacce4
Source dataset: uspto-grants-1997_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05683623

Reaction notes

Loading…