1-Bromohexane → 1,2-Difluoro-3-(hexyloxy)benzene

HRID 2292427Notes

Reaction equation

Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].C(=O)([O-])[O-].[K+].[K+].[F:14][C:15]1[C:20]([F:21])=[CH:19][CH:18]=[CH:17][C:16]=1[OH:22]>>[F:14][C:15]1[C:20]([F:21])=[CH:19][CH:18]=[CH:17][C:16]=1[O:22][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]

Participants

Reactant 3

HCID 81011-Bromohexane

HCID 11430Potassium Carbonate

HCID 808792,3-Difluorophenol

Product 1

HCID 214779521,2-Difluoro-3-(hexyloxy)benzene

Procedure

Quantities: 1-bromohexane (50 g, 0.3 mol), potassium carbonate (83 g, 0.6mol) and compound from Example 37 (39 g, 0.3 mol). The experimental procedure was as described in Example 38.

Sources & evidence

ORD record: ord-090232d563224e52b4cf3842862990fc
Source dataset: uspto-grants-1997_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05683623

Reaction notes

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