Potassium Carbonate → 1,2-Difluoro-3-(heptyloxy)benzene

HRID 2292428Notes

Reaction equation

Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].C(=O)([O-])[O-].[K+].[K+].[F:15][C:16]1[C:21]([F:22])=[CH:20][CH:19]=[CH:18][C:17]=1[OH:23]>>[F:15][C:16]1[C:21]([F:22])=[CH:20][CH:19]=[CH:18][C:17]=1[O:23][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

Participants

Reactant 3

HCID 11430Potassium Carbonate

HCID 123691-Bromoheptane

HCID 808792,3-Difluorophenol

Product 1

HCID 214779471,2-Difluoro-3-(heptyloxy)benzene

Procedure

Quantities: 1-bromoheptane (46.6 g, 0.26 mol), potassium carbonate (70 g, 0.5 mol) and compound from Example 37 (31.2 g, 0.24 mol). The experimental procedure was as described in Example 38.

Sources & evidence

ORD record: ord-64d48ba3b0c14df5adcc77009a2bf53c
Source dataset: uspto-grants-1997_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05683623

Reaction notes

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