Phenylsulphonyl isocyanate → HCID 53939961, compound

HRID 2292629Notes

Reaction equation

HRID 2292629 reaction equation
[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]([C:7]([C:9]2[O:10][C:11]3[C:16]([C:17](=O)[CH:18]=2)=[CH:15][CH:14]=[CH:13][CH:12]=3)=[O:8])=[CH:5][CH:4]=1.[C:22]1([S:28]([N:31]=C=O)(=[O:30])=[O:29])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>C(#N)C>[CH3:1][O:2][C:3]1[CH:21]=[CH:20][C:6]([C:7]([C:9]2[O:10][C:11]3[C:16]([C:17](=[N:31][S:28]([C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)(=[O:30])=[O:29])[CH:18]=2)=[CH:15][CH:14]=[CH:13][CH:12]=3)=[O:8])=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 76096Phenylsulphonyl isocyanateHCID 12752076HCID 12752076, compound

Product 1

HCID 53939961HCID 53939961, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Combine 2-(4-methoxybenzoyl)-chromone (1 mmol) and benzenesulfonyl isocyanate (1.2 mmol) in acetonitrile (7.0 mL). Heat at reflux for 48 hours. Add methanol (5 mL) to quench the reaction. Evaporate in vacuo. Recrystallize to give the title compound.

Workup

  1. temperatureHeat
  2. temperatureat reflux for 48 hours
  3. customAdd methanol (5 mL) to quench
  4. customthe reaction
  5. customEvaporate in vacuo
  6. customRecrystallize

Sources & evidence

ORD record
ord-262fee82fdf24d48ba1ef2d75e0c73cc
Source dataset
uspto-grants-1997_11
Patent number
US05684017

Reaction notes

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