Glycidol → HCID 21478985, compound

Participants

Reaction Steps

A mixture of 4-(1-pyrazolyl)methylphenol [this was obtained by the same method as described in the square parentheses in Production Example 1] (2 g), glycidol (936 g), dry xylene (10 ml) and a catalytic amount of tetramethylammonium chloride was stirred at 60° C. for 6 hours. The reaction mixture was then subjected to silica gel chromatography, which afforded 941 mg of 2-hydroxy-3-[4-(1-pyrazolyl)methylphenoxy]-propanol.

Provenance & Evidence