Methanol → HCID 178439938, compound

HRID 2292746Notes

Reaction equation

HRID 2292746 reaction equation
[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[C:22]3[N:26](C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)[N:25]=[N:24][N:23]=3)=[CH:12][CH:11]=2)[C:7]2[CH:46]=[C:47]([N:50]3[CH2:55][CH2:54][CH2:53][N:52]([CH2:56][C:57]4[CH:62]=[CH:61][CH:60]=[CH:59][CH:58]=4)[C:51]3=[O:63])[CH:48]=[CH:49][C:6]=2[N:5]=1)[CH2:2][CH3:3].CO>Cl>[CH2:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:11]=[CH:12][C:13]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=3[C:22]3[NH:23][N:24]=[N:25][N:26]=3)=[CH:14][CH:15]=2)[C:7]2[CH:46]=[C:47]([N:50]3[CH2:55][CH2:54][CH2:53][N:52]([CH2:56][C:57]4[CH:58]=[CH:59][CH:60]=[CH:61][CH:62]=4)[C:51]3=[O:63])[CH:48]=[CH:49][C:6]=2[N:5]=1)[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 887MethanolHCID 21479273HCID 21479273, compound

Product 1

HCID 178439938HCID 178439938, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

Prepared analogously to Example 55 from 4'-[[2-n-propyl-6-(3-benzyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinon-1-yl)-benzimidazol-1-yl]methyl]-2-(1-triphenylmethyl-tetrazol-5-yl)-biphenyl and methanol in methanolic hydrochloric acid.

Sources & evidence

ORD record
ord-72d4796d174c4a07b8b41b8c5a1d79d4
Source dataset
uspto-grants-1997_11
Patent number
US05684029

Reaction notes

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