Methanol → HCID 178437474, compound

HRID 2292747Notes

Reaction equation

HRID 2292747 reaction equation
[CH2:1]([C:3]1[N:7]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[C:21]3[N:25](C(C4C=CC=CC=4)(C4C=CC=CC=4)C4C=CC=CC=4)[N:24]=[N:23][N:22]=3)=[CH:11][CH:10]=2)[C:6]2[CH:45]=[C:46]([N:49]3[CH2:54][CH2:53][CH2:52][N:51]([CH2:55][C:56]4[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=4)[C:50]3=[O:62])[CH:47]=[CH:48][C:5]=2[N:4]=1)[CH3:2].CO>Cl>[CH2:1]([C:3]1[N:7]([CH2:8][C:9]2[CH:10]=[CH:11][C:12]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[C:21]3[NH:25][N:24]=[N:23][N:22]=3)=[CH:13][CH:14]=2)[C:6]2[CH:45]=[C:46]([N:49]3[CH2:54][CH2:53][CH2:52][N:51]([CH2:55][C:56]4[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=4)[C:50]3=[O:62])[CH:47]=[CH:48][C:5]=2[N:4]=1)[CH3:2]

Participants

4

Reactant 2

HCID 887MethanolHCID 21479325HCID 21479325, compound

Product 1

HCID 178437474HCID 178437474, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

Prepared analogously to Example 55 from 4'-[[2-ethyl-6-(3-benzyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinon-1-yl)-benzimidazol-1-yl]methyl]-2-(1-triphenylmethyl-tetrazol-5-yl)-biphenyl and methanol in methanolic hydrochloric acid.

Sources & evidence

ORD record
ord-23e39b74ba234f65bd0169dd43807711
Source dataset
uspto-grants-1997_11
Patent number
US05684029

Reaction notes

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