Triethylamine → HCID 12635598, compound

HRID 2292833Notes

Reaction equation

HRID 2292833 reaction equation
Cl.[NH2:2][CH2:3][CH2:4][NH:5][C:6]([NH:8][C:9]1[C:14]([Cl:15])=[CH:13][C:12]([N+:16]([O-:18])=[O:17])=[CH:11][C:10]=1[Cl:19])=[S:7].C(N(CC)CC)C>ClCCl>[NH2:2][CH2:3][CH2:4][NH:5][C:6]([NH:8][C:9]1[C:10]([Cl:19])=[CH:11][C:12]([N+:16]([O-:18])=[O:17])=[CH:13][C:14]=1[Cl:15])=[S:7]

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 21479677HCID 21479677, compound

Product 1

HCID 12635598HCID 12635598, compoundYield 80.5%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The thiourea hydrochloride (6) (5.0 g, 14.47 mmole) was suspended in 10 mL of dichloromethane and triethylamine (4 mL, 28.93 mmole) was added in one portion. The mixture was stirred for 4 hours at ambient temperature, and a resulting yellow solid was collected by filtration. The product was dried under vacuum at ambient temperature to provide 3.6 g (80%) of the thiourea (7) as a yellow solid.

Workup

  1. filtrationa resulting yellow solid was collected by filtration
  2. customThe product was dried under vacuum at ambient temperature

Sources & evidence

ORD record
ord-9393acac93234cecb543592cba5262f8
Source dataset
uspto-grants-1997_11
Patent number
US05684156

Reaction notes

Loading…