HCID 21479616, compound → HCID 21479599, compound

HRID 2292968Notes

Reaction equation

HRID 2292968 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH2:13][CH2:12][CH2:11][N:10]([S:14]([C:17]3[CH:22]=[CH:21][C:20]([N+:23]([O-])=O)=[CH:19][CH:18]=3)(=[O:16])=[O:15])[N:9]=2)=[CH:4][CH:3]=1>C(O)(=O)C.[Fe]>[NH2:23][C:20]1[CH:21]=[CH:22][C:17]([S:14]([N:10]2[CH2:11][CH2:12][CH2:13][C:8]([C:5]3[CH:4]=[CH:3][C:2]([Cl:1])=[CH:7][CH:6]=3)=[N:9]2)(=[O:16])=[O:15])=[CH:18][CH:19]=1

Participants

4

Reactant 1

HCID 21479616HCID 21479616, compound

Product 1

HCID 21479599HCID 21479599, compound

Reagents, catalysts & solvents 2

HCID 23925IronCatalystHCID 176Acetic AcidSolvent

Conditions

Temperature
80 °C

Procedure

(4-Chlorophenyl)-1-(4-nitrobenzenesulfonyl)-1,4,5,6-tetrahydropyridazine (2.12 g, 5.60 mmol) was suspended in acetic acid at 80° C. Iron filings (3.0 g) were added to this suspension and the resulting reaction mixture was heated at 80° C. for 30 minutes and filtered. Upon cooling the title compound precipitated out of this mixture as a solid: mp 205°-206° C.

Workup

  1. customthe resulting reaction mixture
  2. filtrationfiltered
  3. temperatureUpon cooling the title compound
  4. customprecipitated out of this mixture as a solid

Sources & evidence

ORD record
ord-17375845ecea45d2b28eda80fba17294
Source dataset
uspto-grants-1997_11
Patent number
US05684151

Reaction notes

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