Hydrochloric Acid → 1-Triethoxysilylglycerol

HRID 2292998Notes

Reaction equation

Cl[Si:2]([O:9][CH2:10][CH3:11])([O:6][CH2:7][CH3:8])[O:3][CH2:4][CH3:5].C1(NC2CCCCC2)CCCCC1.Cl[SiH3].Cl.[OH:28][CH2:29][CH:30]([CH2:32][OH:33])[OH:31]>>[CH2:4]([O:3][Si:2]([O:9][CH2:10][CH3:11])([O:6][CH2:7][CH3:8])[O:28][CH2:29][CH:30]([CH2:32][OH:33])[OH:31])[CH3:5]

Participants

Reactant 5

HCID 313Hydrochloric Acid

HCID 753Glycerol

HCID 7582Dicyclohexylamine

HCID 61622Chlorosilane

HCID 78398Triethoxychlorosilane

Product 1

HCID 544271121-TriethoxysilylglycerolYield 90%

Procedure

Glycerol (GL) was reacted with chlorotriethoxysilane (CTS) in a 1:1 ratio at 0° C. in a 50/50 mixture of ethanol/cyclomethicone, using a 1:1 ratio of dicyclohexylamine to chlorosilane as the HCl scavenger. The resulting product, 1-triethoxysilylglycerol, was obtained in 90% yield and was dissolved to a 10% by weight solution in a 50/50 by volume mixture of ethanol/cyclomethicone.

Sources & evidence

ORD record: ord-d646d02b3fc448f9809f9b7ce32c63c9
Source dataset: uspto-grants-1997_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05686065

Reaction notes

Loading…