反应详情

To a mixture containing 11.7 g of fluoroacetic acid (0.15M), 27.3 ml of dicyclohexylcarbodiimide(0.17M) and 200 ml of dichloromethane was dropwise added 17 ml of phenethylamine(0.17M), which was stirred for 12 hours. The solids produced were filtered and the filtrate was washed with water, dried over anhydrous sodium sulfate and concentrated. The residue was purified by silica gel column chromatography to give 11.9 g of the title compound as white solids.

1. customThe solids produced
2. filtrationwere filtered
3. washthe filtrate was washed with water
4. dry with materialdried over anhydrous sodium sulfate
5. concentrationconcentrated
6. customThe residue was purified by silica gel column chromatography