HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methylisoquinoline → 3-Methyl-1,2,3,4-tetrahydroisoquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methylisoquinoline | HCID 14306 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3-Methyl-1,2,3,4-tetrahydroisoquinoline | HCID 568974 | 107% |
Reaction Steps
3.0 g of 3-methylisoquinoline(21 mM) and 50 ml of methanol were mixed and 0.84 g of platinum oxide was added thereto. The mixture was subjected to hydrogenation at 40 psi and filtered. The filtrate was concentrated under a reduced pressure, to give 3.3 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05686458 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-1e19945c3f7a45258bb9d02c007a1002 |
| Source note | uspto-grants-1997_11 |