Anthranilic Acid → HCID 178518333, compound

Participants

Reaction Conditions

Reaction Steps

To a mixture containing 41 g of 2-aminobenzoic acid (0.3M), 21 of water and 34 ml of acetic acid, was dropwise added 54 g of potassium cyanate dissolved in 200 ml of water. The resultant was stirred for an hour and slowly added with 60 g of 0.3M aqueous sodium hydroxide so as not to exceed the reaction temperature of 40° C. The solution, while heated to 90° C., was stirred for 30 minutes, and then cooled to 0° C. The resultant was acidified by adding a concentrated hydrochloric acid and the solids thus produced were filtered to obtain 43.7 g of the title compound.

Provenance & Evidence