Aniline → HCID 21476495, compound

HRID 2293146Notes

Reaction equation

HRID 2293146 reaction equation
[Cl:1][C:2]1[N:11]=[C:10]([N:12]2[CH2:21][CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:13]2)[C:9]2[C:4](=[C:5]([O:22][CH3:23])[CH:6]=[CH:7][CH:8]=2)[N:3]=1.[NH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>CN(C)C=O>[ClH:1].[CH3:23][O:22][C:5]1[CH:6]=[CH:7][CH:8]=[C:9]2[C:4]=1[N:3]=[C:2]([NH:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[N:11]=[C:10]2[N:12]1[CH2:21][CH2:20][C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:13]1

Participants

4

Reactant 2

HCID 6115AnilineHCID 21476505HCID 21476505, compound

Product 1

HCID 21476495HCID 21476495, compoundYield 73%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In accordance with the same procedures as in Example 18, except that to a mixture of 1.5 g of the compound (4.6 mM) prepared in Example 4 and 15 ml of dimethylform-amide, 0.65 ml of aniline(6.9 mM) was added, 1.40 g of the title compound was prepared.

Workup

  1. additionwas added

Sources & evidence

ORD record
ord-860add903f7142d1aebf3d9c9b593bb8
Source dataset
uspto-grants-1997_11
Patent number
US05686458

Reaction notes

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