Triethylamine → N-[4-(6,7-Dihydro-dibenzo[b,d]azepine-5-carbonyl)-phenyl]-2-methyl-benzamide

HRID 2293246Notes

Reaction equation

HRID 2293246 reaction equation
[CH3:1][C:2]1[CH:19]=[CH:18][CH:17]=[CH:16][C:3]=1[C:4]([NH:6][C:7]1[CH:15]=[CH:14][C:10]([C:11](Cl)=[O:12])=[CH:9][CH:8]=1)=[O:5].[CH:20]1[C:30]2[C:29]3[CH:31]=[CH:32][CH:33]=[CH:34][C:28]=3[CH:27]=[CH:26][NH:25][C:24]=2[CH:23]=[CH:22][CH:21]=1.C(N(CC)CC)C>>[CH:20]1[C:30]2[C:29]3[CH:31]=[CH:32][CH:33]=[CH:34][C:28]=3[CH2:27][CH2:26][N:25]([C:11]([C:10]3[CH:14]=[CH:15][C:7]([NH:6][C:4](=[O:5])[C:3]4[CH:16]=[CH:17][CH:18]=[CH:19][C:2]=4[CH3:1])=[CH:8][CH:9]=3)=[O:12])[C:24]=2[CH:23]=[CH:22][CH:21]=1

Participants

4

Reactant 3

HCID 8471TriethylamineHCID 107074414-[(2-methylbenzoyl)amino]benzoyl ChlorideHCID 160701625H-Dibenz[b,d]azepine

Product 1

HCID 44212554N-[4-(6,7-Dihydro-dibenzo[b,d]azepine-5-carbonyl)-phenyl]-2-methyl-benzamide

Procedure

As described for Example 2, 1 mmol of 4-[(2-methylbenzoyl)amino]benzoyl chloride, 1 mmol of 5H-dibenz[b,d]azepine and 2 mmol of triethylamine are stirred at room temperature for 5 hours to give the product as a pale yellow solid.

Sources & evidence

ORD record
ord-e0285c792b714d6db88569d9c5f26681
Source dataset
uspto-grants-1997_11
Patent number
US05686445

Reaction notes

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